Endocrine Abstracts

Introduction: The aim of this study was to determine frequency of lymphonodal metastases in jugulo-carotid chain (JCC) and central neck compartment in incidental thyroid microcarcinomas (ITMC), as well as to examine whether sentinel lymph node (SLN) biopsy of JCC is an accurate technique to select patients with true positive, but clinically and ultrasonically negative lymph nodes, for modified radical neck dissection (MRND).Materials and methods: Out of ...

Introduction: Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy (80%), while primary thyroid lymphomas (PTL) occur in only 0.6–5% of cases. A significant number of PTCs, as well as PTLs, arise in the setting of Hashimoto’s thyroiditis (HT), however the simultaneous occurrence of these two malignancies is extremely rare.Case report: We present a 34-year-old female patient with thyroid MALT lymphoma and coexisting papillary ...

Introduction: The aim of this study was to determine whether sentinel lymph node (SLN) biopsy of jugulo-carotid chain (JCC) in thyroid microcarcinomas (TMC) is an accurate technique to select patients with true positive, but clinically and ultrasonically N0 LNs, for modified radical neck dissection (MRND).Materials and methods: In total 199 patients with TMC underwent total thyroidectomy, central neck dissection and SLN mapping with 0.2 ml of 1% methylen...

Background: Papillary thyroid carcinoma in children and adolescents is rare but it shows aggressive behavior. Gross lymph node metastases and distant metastases are common on first clinical presentation.Patients and methods: Forty-eight children and adolescents were operated due to PTC. Mean age was 16.6 years (range 7–21). At the time of diagnosis 13% had lung metastases. Total thyroidectomy or completion of thyroidectomy was performed in all cases...

Subclinical hyperthyroidism (ScHyper) is a condition with suppressed TSH, and normal free T3 and free T4 hormones, affecting 10% of the population. There are two subgroups of patients, the first group with TSH lower than 0.1 U/l, and the second group with mildly suppressed TSH between 0.1 and the lower assay reference limit. The patients from the first group should be treated, but there is no evidence for therapy for the second group of patients.We prese...

Objective: Our goal was to investigate the effects of glucose levels from 75-g oral glucose tolerance test (OGTT) on large for gestational age (LGA) newborns in women with gestational diabetes mellitus (GDM).Material and methods: A prospective study was undertaken in Outpatient Department of Clinics for Endocrinology, Diabetes and Metabolic Disorders. One hundred and eighteen pregnant women were prospectively screened for GDM between 24 and 28 weeks of p...

Introduction: Glucagonoma is a rare condition with annual incidence 1 in 20 million, associated with diabetes mellitus, dermatitis, deep vein trombosis and depression.Case report: A 55-year-old woman patient was hospitalized at our department because of intense discomfort of the skin lesions that were pruritic and painful, erythematous area of skin with blisters that breach after a few days, red tongue, cracks on the mouth corners. She had a constant wei...

Aim/hypothesis: Chronic renal failure maintenance hemodialysis (HD) patients are at risk for low bone mineral density (BMD) and fractures. Parathyroid hormone (iPTH) plays a pivotal role in the pathophysiology of uremic bone disease, but in healthy population body weight and particularly body composition are more important determinants of bone mass.Patients and methods: We studied BMD (results were recorded as g/cm2) and T score using D...

Objective: Hot flushes and night sweats experienced by 60–70% of postmenopausal women are considered as classical signs of menopause. Estrogens is the gold standard treatment, but in view of its potential risks, various herbal preparations and vitamin supplements have a great appeal to women. Aim of this study was to assess the effect of a nutritional supplement (Menopace®) on the frequency and severity of hot flushes and the quality of life in postmenopausal women i...

Hyperprolactinaemia is the most common disturbance in the pituitary gland function. Different physiological and patological conditions could influnce prolactin (PRL) secretion. Prolactin secreting tumors (micro and macroprolactinomas) are rare in children and adolescents (estimated incidence is 1 per milion). Functional diversity of prolactin action is responsable for different initial clinical expression of hyperprolactinaemia.We investigated causes of ...